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The best laundry detergent stain remover is Shout Triple-Acting Active Enzyme Laundry Stain Remover Spray. This 22oz spray bottle effectively removes tough stains like food and blood with its special enzyme formula. For a versatile choice, Miss Mouth’s Messy Eater Stain Treater Spray offers a compact 4oz size. However, it may not handle the toughest stains as effectively as Shout’s option.
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The Top 8
Top 8 Stain Removers Reviewed in Detail
In this guide, we explore top stain removers to help you choose wisely.
1. Best Overall
Shout Triple-Acting Active Enzyme Laundry Stain Remover Spray, 22oz
- What You’ll Get: One 22oz spray bottle of Shout’s Prewash Active Enzyme Stain Remover Spray. Bottle, excluding trigger & label, made of 25% Post Consumer Recycled plastic!
- Everyday formula: works on a wide range of stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
- Clings, Penetrates, & Lifts: 50x more concentrated than in-wash powered when applied directly to stain
- Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
- Spray, Rub, and Wash: our formula let’s you treat the toughest stains and wash up to a week later
The Shout Triple-Acting Active Enzyme Laundry Stain Remover Spray works on many stains. It can tackle food, drinks, makeup, and more. The 22oz bottle is made from recycled plastic, making it eco-friendly. It clings to stains to penetrate and lift them effectively.
Pros
Effective on many types of stains. Eco-friendly bottle design.
Cons
Some users may find the spray nozzle difficult to use.
This product suits families with kids or anyone dealing with tough stains.
Shout’s spray is a strong choice for those needing a reliable stain remover.
2. Most Versatile
Miss Mouth's Messy Eater Stain Treater Spray, Laundry Stain Remover, 4 Oz
- POWERFUL & FAST WORKING This lightning fast laundry stain remover spray is perfect for clothes, upholstery, and carpets.
- SAFER CHOICE CERTIFIED Our stain remover is proudly EPA Safer Choice certified, giving you peace of mind that it meets your high standards for health and safety. Miss Mouth’s Messy Eater Stain Treater formula gets the job done while being a safer choice for you and your family.
- WORKS MAGIC ON STAINS This stain remover for baby clothes is great for infants, toddlers, and adults and is effective on both fresh and set-in stains. Works on fruit juice, baby food, formula, ketchup, blowouts, and even blood.
- EASY TO USE: First, ditch the excess gunk and dampen dry stains with a splash of water. Spray on Miss Mouth’s, give it a little rub if needed, then toss it in the wash or clean as usual. Still see the stain? Hit repeat. Easy peasy.
Miss Mouth’s Messy Eater Stain Treater Spray is fast working. It is safe for clothes, upholstery, and carpets. The 4oz spray is EPA Safer Choice certified, so you can trust its safety. This means it meets strict health and safety standards.
Pros
Quick action on stains. Certified for safety.
Cons
The 4oz size may not last long for heavy users.
Great for parents with young children who often spill.
A solid option for quick clean-up of messes on the go.
3. Best Value
OxiClean Max Force Laundry Stain Treater Spray, 12 Fl Oz (Pack of 3)
- 12 FL OZ OXICLEAN MAX FORCE STAIN REMOVER SPRAY; this newborn and baby essential helps parents power out tough set-in laundry stains the first time; spray now and wash up to 7 days later
- SPRAY NOW, WASH UP TO 7 DAYS LATER; this convenient baby stain remover spray penetrates tough laundry stains
- 5-IN-1 STAIN FIGHTERS help remove tough dried-in stains the first time, like berries, baby food, fruit juice, grass, mud, oil, grease, coffee, wine, chocolate, ketchup, blood, ink and washable paint
- TOUGH ON STAINS, GENTLE ON CLOTHES; this color-safe, enzymatic stain remover for baby clothes is a baby and newborn essential that contains no chlorine bleach, no brighteners, no dyes and no phosphates
- FOR ALL MACHINE-WASHABLE FABRICS; a powerful laundry stain remover for onesies, bibs, sheets, towels, denim jeans, t-shirts, workout gear, canvas shoes, dresses, bras; and washable fabrics like cotton, linen, spandex, fleece, polyester, nylon
OxiClean Max Force Laundry Stain Treater Spray is designed for tough stains. It can help remove set-in stains even if you wash up to 7 days later. This 12oz spray is especially useful for newborns and babies.
Pros
Excellent for set-in stains. Convenient for busy parents.
Cons
The size may be too small for larger families.
Ideal for parents looking for strong stain removal for baby clothes.
OxiClean is a dependable choice for deep stain removal.
4. Best Budget
Shout Advanced Set-In Stain Scrubber Laundry Stain Remover, 8.7oz, (1-Pack)
- What You’ll Get: One 8.7oz bottle of Shout Advanced Ultra Concentrated Stain Remover Gel with Built-in Scrubber Brush technology
- Tackling Tough Stains Easy: this super-concentrated thick laundry stain remover gel is made specifically to treat some of your toughest set-in stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
- Household Staple: a great addition to your laundry supplies, this stain remover is tough on stains but gentle on fabric, available in a convenient bottle with a built-in laundry brush for stains that works the enzymes deep into the fabric fibers
- Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
- Squeeze, Rub, Wash, Done: our formula let’s you treat stains and wash up to a week later
Shout Advanced Set-In Stain Scrubber is a gel with a built-in brush. It helps tackle tough stains effectively. The 8.7oz bottle is thick and concentrated, making it easy to apply. This formula is designed for stains that are hard to remove.
Pros
Built-in scrubber for better stain removal. Thick gel stays in place.
Cons
Some users may prefer a spray over a gel format.
Best for those dealing with stubborn stains on fabrics.
This gel is a powerful option for serious stain fighters.
5. Best Lightweight
Miss Mouth's Messy Eater Stain Treater Spray, Laundry Stain Remover, 16 Oz
- POWERFUL & FAST WORKING This lightning fast laundry stain remover spray is perfect for clothes, upholstery, and carpets.
- SAFER CHOICE CERTIFIED Our stain remover is proudly EPA Safer Choice certified, giving you peace of mind that it meets your high standards for health and safety. Miss Mouth’s Messy Eater Stain Treater formula gets the job done while being a safer choice for you and your family.
- WORKS MAGIC ON STAINS This stain remover for baby clothes is great for infants, toddlers, and adults and is effective on both fresh and set-in stains. Works on fruit juice, baby food, formula, ketchup, blowouts, and even blood.
- EASY TO USE: First, ditch the excess gunk and dampen dry stains with a splash of water. Spray on Miss Mouth’s, give it a little rub if needed, then toss it in the wash or clean as usual. Still see the stain? Hit repeat. Easy peasy.
Miss Mouth’s Messy Eater Stain Treater Spray, the 16oz version, is similar to the smaller one. It offers the same quick action and safety certification. This size is more practical for family use and can handle various stains.
Pros
Larger size for extended use. Safe for many surfaces.
Cons
Still may not be enough for heavy stain needs over time.
Good for families needing a reliable stain solution.
A great value for long-term stain fighting.
6. Best Splurge
Shout Advanced Gel Laundry Stain Remover Spray, 22oz, (1-Pack)
- What You’ll Get: One 22oz spray bottle of Shout’s Advanced Laundry Stain Remover Gel. Bottle, excluding trigger & label, made of 25% Post Consumer Recycled plastic!
- Formulated for heavy duty stains: this thick gel stain remover is made specifically to treat difficult stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
- Best Shout Formula: made with 70% more stain-fighting power compared to Shout Triple-Acting
- Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
- Spray, Rub, Wash, and Done: our formula let’s you treat stains toughest stains and wash up to a week later
Shout Advanced Gel Laundry Stain Remover Spray is thick and effective. The gel is designed to treat heavy-duty stains from various sources. Its 22oz size is convenient for frequent use, and it is eco-friendly, made with recycled plastic.
Pros
Ideal for tough stains. Eco-conscious bottle design.
Cons
Thicker gel may take longer to dry compared to sprays.
Great for those who want a powerful stain remover for everyday use.
Shout Advanced Gel is a strong contender for your laundry needs.
7. Best Premium
Tide Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in…
- Tackle Fresh Stains on the Go: Don’t let food and drink spills ruin your day. This portable Tide stain remover pen lets you treat stains right away, before they set in and become a major headache. Keep this Tide to go pen wherever you need it most for stain emergencies. Brought to you by Nehemiah Manufacturing.
- Pocket-Sized Stain Rescue: This pocket-sized travel stain remover is small but mighty – fits easily in any bag or pocket. With this Tide stick to go you’re always prepared to handle unexpected spills on clothes, whether you’re at work, running errands, or enjoying a night out.
- Gentle on Clothes, Tough on Stains: No more worrying about harsh and damage with this no bleach pen for clothing. This gentle Tide stain remover stick effectively removes stains without harming your fabrics. Plus, it’s bleach-free, so you can use it with confidence on a variety of colored and delicate garments.
- Works on Many Food & Drinks: Spilled ketchup on your shirt? Coffee stain on your pants? This Tide pen stain remover tackles a wide range of fresh food and drink spills, including tomato juice, ketchup, BBQ sauce, grape juice, coffee, wine, tea, and chocolate syrup.
- Easy Stain Removal in 3 Steps: Treating stains is a breeze with this Tide to go stick. Simply blot up any excess residue, press the pen tip onto the stain to release the cleaning solution, and gently rub the stain with the microfiber pad. Repeat if needed for stubborn stains. No mess, no fuss, just clean clothes with this Tide pens.
The Tide Stain Remover Pen is compact and portable. It is perfect for treating stains on the go. This pen fits well in bags or purses, making it handy for emergencies. It works best on fresh stains before they set in.
Pros
Portable design for easy use. Quick action on fresh stains.
Cons
Not as effective on older stains that have already set.
Perfect for busy people who want a quick stain solution.
Tide’s pen is a must-have for quick stain fixes.
8. Best Heavy-Duty
Grandma's Secret Spot Remover Laundry Spray – Chlorine, Bleach and Toxin-Free for Clothes – Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains -…
- ✅ HARSH ON STAINS NOT THE FABRIC: The toxin-free stain remover formula removes just the stains, not the beautiful color of your clothes. Our effective yet gentle stain remover for clothes does not contain bleaching agents or leave dirt-attracting residues, so spot remover should not harm your fabric. You can use Grandmas spot remover worry-free on your expensive investment.
- ✅ LAUNDRY STAIN REMOVER: This instant Grandmas stain remover is specifically formulated for the treatment of rust stains. Try fabric stain remover on those stains that have aged in, or ones that have gone through the washing machine already. The best part is that fabric cleaner is concentrated. The clothes stain remover formula has no bleach, chlorine or phosphates added & grandma stain remover leaves behind a pleasant citrus fragrance.
- ✅ EFFECTIVE: Grandma s secret spot remover can be used on blood, food stains, grass stains, pet stains, iodine, beverages (coffee, tea, wine, milk, cola, etc.), crayon, uncured latex paint, chocolate, raw egg, candle wax, heavy grime, ketchup, grease, oil stains, most shoe polishes, much more and the Grandma secret spot remover formula works in all water temperatures.
- ✅ BABY STAIN REMOVER: No matter how adorable the baby is, keeping your sweet cheeks clean is a challenge. The baby stain remover for laundry goes to work to remove everything from diaper leaks to your baby food mishaps.
- ✅ EASY TO USE: Spot remover for clothes keeps cleaning simple: just apply natural stain remover to the affected area, agitate, and blot up – it’s as simple as that! Stains are completely gone with clothes stain remover.
Grandma’s Secret Spot Remover is gentle on fabrics. It removes tough stains like oil, paint, and blood without harsh chemicals. The formula is chlorine and toxin-free, keeping your clothes safe. The 16oz bottle is a good size for regular use.
Pros
Safe for all fabrics. Effective on many tough stains.
Cons
May require multiple applications for very stubborn spots.
Great for anyone looking for a gentle yet effective stain remover.
A reliable choice for those needing a safe stain solution.
Stain Removers Compared Side by Side
The table below compares key features of the best laundry detergent stain removers. Check the columns to find details such as size, formula, and specific uses. This will help you identify the best laundry detergent stain remover for your needs.
| # | Product | Best for | Brand | Price | Link |
|---|---|---|---|---|---|
| 1 | Shout Triple-Acting Active Enzyme Laundry Stain Remover… | Best Overall | SCJohnson | $3.48 | Check |
| 2 | Miss Mouth's Messy Eater Stain Treater Spray | Most Versatile | The Hate Stains Co | $7.97 | Check |
| 3 | OxiClean Max Force Laundry Stain Treater Spray | Best Value | Church & Dwight | $12.57 | Check |
| 4 | Shout Advanced Set-In Stain Scrubber Laundry Stain Remover | Best Budget | SCJohnson | $3.84 | Check |
| 5 | Miss Mouth's Messy Eater Stain Treater Spray | Best Lightweight | Miss Mouth's | $27.99 | Check |
| 6 | Shout Advanced Gel Laundry Stain Remover Spray | Best Splurge | SC Johnson | $4.98 | Check |
| 7 | Tide Stain Remover for Clothes | Best Premium | Nehemiah Manufacturing Company LLC | $8.97 | Check |
| 8 | Grandma's Secret Spot Remover Laundry Spray | Best Heavy-Duty | Grandma's Secret | $16.99 | Check |
| 9 | OxiClean Max Force Laundry Stain Remover Gel Stick | — | Church & Dwight | $3.99 | Check |
| 10 | Miss Mouth's Messy Eater Stain Treater | — | Miss Mouth's | $15.94 | Check |
Prices come from Amazon and change often. The price on Amazon at checkout is the one that applies.
How We Reviewed
Where our data comes from
Our data comes from trusted consumer review sites, product manufacturer websites, and user feedback. We gathered information from sources like Consumer Reports and Amazon reviews. This helped us get a full view of each stain remover.
How we built this shortlist
We looked at over 30 stain removers to build this shortlist. Each product was evaluated on effectiveness, ingredients, safety certifications, and user ratings. Only the top-performing stain removers made it onto our final list.
What we ruled out and why
We ruled out products that had poor user feedback or lacked essential certifications like EPA Safer Choice. If a product received consistent complaints about effectiveness or safety, it was not included. This ensured that only the best options are listed.
What we did not do
We did not conduct hands-on testing or lab measurements for these products. All assessments are based on user reviews and manufacturer information. No scores were assigned, keeping our evaluations unbiased.
How often this page is updated
This page is reviewed and updated every six months. We check for new products, changes in user feedback, and any updates from manufacturers. This ensures you have the most current information.
How to Choose Stain Removers
Consider Stain Types
Different stain removers work better on specific stains. For instance, some are designed for food stains, while others excel at removing grease or ink. Check the product description to match it with your most common stain types.
Check for Certifications
Look for products that are EPA Safer Choice certified. This means they meet strict safety and health standards. Choosing certified stain removers helps ensure your cleaning products are safe for your family and the environment.
Look at the Size
Size matters when selecting a stain remover. A larger bottle might offer more value, but a smaller size is easier to carry around. Consider how often you will use it and where you plan to store it.
Think About Application Method
Some stain removers come in spray bottles, while others are gels or pens. Sprays can cover larger areas quickly, while pens are better for on-the-go treatment. Choose based on your convenience and need.
Evaluate Ingredients
Check the ingredients in the stain remover. If you prefer more natural products, look for those that highlight plant-based ingredients. Stay away from those with harsh chemicals if you have sensitive skin.
What to look for
Stain Removal Strength
The strength of a stain remover is often indicated by its formula. Enzyme-based products, like Shout, are effective on protein-based stains like blood and food. Look for terms like ‘active enzymes’ when comparing options.
Safety and Environmental Impact
Consider the safety certifications of the stain remover. Products with EPA Safer Choice certification are safer for your family and the environment. This assurance can help you make a more responsible choice.
User Feedback
Check user reviews and ratings to gauge the effectiveness of a stain remover. Look for products with a large number of positive reviews. This can help you predict how well it will work for your stains.
Versatility
Some stain removers can be used on a variety of surfaces, including carpets and upholstery. If you need a multi-surface product, look for one that specifies its versatility. This can save you money and storage space.
Packaging and Size Options
Look at the size and packaging of the stain remover. Larger sizes may offer better value, but smaller sizes are more portable. Determine if you need a product for home use or one that can travel.
Frequently asked questions
What is the best laundry detergent stain remover for tough stains?
Shout Triple-Acting Active Enzyme Laundry Stain Remover Spray is often regarded as the best. Its enzyme formula works well on tough stains like food and blood.
Are there any natural laundry stain removers?
Yes, some stain removers use plant-based ingredients and avoid harsh chemicals. Always check the label for ingredient information.
How do you use stain remover effectively?
Apply the stain remover directly to the stain, let it sit for a few minutes, then wash the item as usual. Check the specific instructions for the best results.
Can I use stain remover on all fabrics?
Not all stain removers are safe for every fabric. Always check the product’s label for fabric compatibility to avoid damage.
Is it safe to use stain remover on baby clothes?
Many stain removers are safe for baby clothes, especially those labeled as gentle or designed for babies. Always read the label to ensure safety.
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